Filariasis in the Pacific

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Application of the Filariasis CELISA Antifilarial IgG4 Antibody Assay in Surveillance in Lymphatic Filariasis Elimination Programmes in the South Pacific

Elimination of lymphatic filariasis (LF) in the Pacific Island Countries and Territories (PICT) has been defined as <0.1% circulating filarial antigen (CFA) prevalence in children born after the implementation of successful mass drug administrations (MDAs). This research assessed the feasibility of CFA and antibody testing in three countries; Tonga, Vanuatu, and Samoa. Transmission is interrupt...

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BACKGROUND Lymphatic filariasis (LF) is a leading cause of disability in South Pacific regions, where >96% of the 1.7 million population are at risk of LF infection. As part of current global campaign, mass drug administration (MDA) has effectively reduced lymphatic filiariasis prevalence, but mosquito vector biology can complicate the MDA strategy. In some regions, there is evidence that the g...

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ژورنال

عنوان ژورنال: Nature

سال: 1951

ISSN: 0028-0836,1476-4687

DOI: 10.1038/168776a0